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Dr. Erick H. Alayo CV

Education

Master in Management of Social Programs and Projects
2001

Specialization in Statistics for Research
2001

Medical Doctor
2000

Cayetano Heredia University, Lima, Peru

Residency Training

Internal Medicine Internship-Residency 
2003 – 2006

John Stroger Jr. Hospital of Cook County, Chicago, Illinois

Board Certified in Internal Medicine
2006 – 2016

Gastroenterology Fellowship –  ERCP/ EUS training 
2006 – 2009

John Stroger Jr. Hospital of Cook County, Chicago, Illinois

Board Certified in Gastroenterology 
2009 – 2019

Hospital Affiliations

Scripps Mercy Hospital- Chula Vista.
2009-present

Sharp Chula Vista Medical Center.
2009-present

Clinical Trials

Sub Investigator: SPD476-313 SHIRE PHARMACEUTICALS-A Phase III, Randomized, Double-Blind, Dose-Response, Stratified, Placebo-Controlled Study Evaluating the Safety and Efficacy of SPD476 versus Placebo over 104 weeks in the Prevention of Recurrence of Diverticulitis

Sub Investigator:   ASMP3001: TIOGA Pharmaceuticals, Inc. A 12-Week Randomized, Double-Blind, Placebo-Controlled Study of Asimadoline in Subjects With Diarrhea-Predominant Irritable Bowel Syndrome (D-IBS). 9/2010

Sub Investigator: PA32540-301: POZEN Pharmaceuticals. A 6-Month, Phase 3, Randomized, Double-Blind, Parallel-Group, Controlled, Multi-Center Study to Evaluate the Incidence of Gastric Ulcers Following Administration of Either PA32540 or Enteric Coated Aspirin 325 mg in Subjects Who Are at Risk for Developing Aspirin-Associated Ulcers April 2010

Sub Investigator: BUCF3002: SALIX Pharmaceuticals: A Phase 3, Randomized, double blind placebo controlled multicenter study to assess the efficacy and safety of budesonide foam ( 2mg/25ml bid for 2 weeks, followed by 2mg/25 ml qd for 4 weeks) versus placebo in subjects with active mild to moderate ulcerative proctitis or proctosigmoiditis

Sub Investigator:  BFPS3073 SALIX Pharmaceuticals – A Phase 3, Open Label, Multicenter Study to Assess the Safety and Tolerability of Budesonide Foam in Subjects with Active Ulcerative Proctitis or Proctosigmoiditis: September 2011 – present (1 randomized)

Sub Investigator:  SP-SP304202-10 SYNERGY Pharmaceuticals – A Phase IIb Randomized, Double-Blind, Placebo-Controlled, 28-Day Repeat, Oral, Dose-Ranging Study to Assess the Safety and Pharmacodynamic Effects of SP-304 in Patients with Chronic Idiopathic Constipation. 10/2011 – ongoing (40 screened/20 randomized)

Sub Investigator:  27018966IBS3002 Furiex – A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy, Safety and Tolerability of JNJ-27018966 in the Treatment of Patients with Diarrhea-Predominant Irritable Bowel Syndrome: May 2012 – ongoing (5 screened/ 3 randomized)

Sub Investigator:  RFIB3053 Salix – A Study to Assess Repeat Treatment Efficacy and Safety of Rifaximin 550 mg TID in Subjects with Irritable Bowel Syndrome with Diarrhea (IBS-D): June 2012 – ongoing (7 screened/1 randomized)

Sub Investigator: SP304-20212 SYNERGY Pharmaceuticals- A Randomized, 12-Week, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Assess the Safety and Efficacy of Plecanatide in Patients with Irritable Bowel Syndrome with Constipation (IBS-C)

Research Experience

Research Physician 
2000 – 2002

AB PRISMA, Lima, Peru

“Epidemiology of Helicobacter pylori infection in Lima.”

“Helicobacter pylori infection in Peruvian patients and in patients of Japanese ascendance residents in Peru.”

Latent pulmonary tuberculosis in autopsied humans: Molecular, bacteriologic and pathologic studies.”

Research Physician
2000 – 2002

Alexander von Humbolt Institute of Tropical Medicine, Lima, Peru

“The Influence of the El Niño phenomenon on the epidemiology of Vector transmitted diseases.”

Consultant – Medicine and Odontology (undergraduate & graduate theses) 
1998 – 2002

Cayetano Heredia University (UPCH), Lima Peru

Physician – Rural Service
2000 – 2001

Peruvian Ministry of Health, Lima, Peru

Physician
2000 – 2001

“San Jose” Clinical Center, Lima, Peru

Co-Investigator – Gastrointestinal Physiology Working Group
1997 – 2000

Cayetano Heredia and Johns Hopkins Universities, Lima, Peru

Co-Investigator – Endocrinology Laboratory
1997 – 2000

Cayetano Heredia University, Lima, Peru

Co-Investigator – Ophthalmology 
1997 – 1999

Arzobispo Loayza Hospital, Lima, Peru

Teaching Experience

Teacher of Physiopathology
2000 – 2001

Teacher of Medical English
2000 – 2001

Teacher of Microbiology and Histology
1998 – 2000

Medical Technology School, Faculty of Medicine “Alberto Hurtado”

Cayetano Heredia University (UPCH), Lima, Peru

Editorial Assignments

Reviewer                                                                                                                                             

Critical Care Medicine ¨Emerging Infectious Diseases¨  CHEST

“American Journal of Tropical Medicine and Hygiene¨ British Medical Journal

Gastroenterology ¨Clinical Gastroenterology and Hepatology”  2003 – present

Awards and Scholarships

  • First Prize, National Research Project Convocation, CONCYTEC, 2002
  • National Award in Investigation in Medicine ABEEFE Bristol-Myers, 2001
  • Scholarship, “School of Public Health-UPCH,” Master in Management of Social Programs and Projects, 2000-2001
  • Scholarship, “Statistics Department-UPCH,” Specialization in Statistics for Research, 2000-2001
  • National Award in Investigation in Pediatrics HERSIL, 2000
  • National Award AVENTIS for the Best Article Published in a Peruvian Journal, 2000
  • Second Prize for the Best Presentation, National Congress of Internal Medicine, 2000
  • First Prize for the Best National Research in Health Sciences, “HIPÓLITO UNANUE,” 2000
  • National Award in Investigation in Medicine ABEEFE Bristol-Myers, 1999
  • “Honor to Success” Award, Procter & Gamble, 1998
  • Second Prize, National Competition of Ophthalmologic Research, 1998

Grants

  • “Variation in the H. pylori prevalence and its relation with the chloride levels in water of Lima, Peru,” (1985 to 2002), funded by CONCYTEC-Peru, 2002
  • The Influence of the El Niño phenomenon on the epidemiology of Bartonellosis in the Peruvian Department of Ancash,” funded by CONCYTEC-Peru, 2001
  • “Prevalence of Lactose Intolerance in Peruvian Children,” funded by The Child Health Institute of North America, 1999

Publications

Alayo E, Attar B, Go B. A Case of Recurrent Abdominal Pain Due to a Gossypiboma With Spontaneous Resolution. Clin Gastroenterol Hepatol. 2009 Sep 3

Ramírez-Ramos A, Watanabe-Yamamoto J, Takano-Morón J, Gilman RH, Recavarren Arce S, Arias-Stella J, Yoshiwara-Wakabayashi E, Rodríguez-Ulloa C, Miyagui-Maeda J, Alayo E, et al. Decrease in prevalence of peptic ulcer and gastric adenocarcinoma at the Policlínico Peruano Japones, Lima, Peru, between the years 1985 and 2002. Analysis of 31,446 patients. Acta Gastroenterol Latinoam. 2006 36:139-46;

Ramírez-Ramos A, Gilman RH, Watanabe-Yamamoto J, Takano-Moron J, Arias-Stella J, Yoshiwara-Wakabayashi E, Rodríguez-Ulloa C, Miyagui-Maeda J, Velapatiño-Cochachi B, Mendoza-Requena D, Alayo E, et al. Comparison of the prevalence of Helicobacter pylori stomach infection in Peruvian and Japanese population. Acta Gastroenterol Latinoam. 2005;35:219-24.

León-Barúa R, Recavarren S, Alayo E, Gilman R. Helicobacter pylori-associated chronic atrophic gastritis probably predisposing to severely dehydrating diarrheal disease by Vibrio Cholera.  Trans R Soc Trop Med Hyg. 2006;100:567-72.

Alayo E, Villena J, Evans A,  Zimic M. Can hormone levels improve the ability to predict intensive care unit mortality?  Intensive Care Medicine July 2005.

Recavarren S, Ramirez Ramos A, Gilman R , Alayo E. Severe Helicobacter pylori-associated gastritis in the Peruvian Andes.  Histopathology 2005;46, 374-379.

Alayo E, Huarcaya E, Nasarre C, del Aguila R, Llanos A. The Influence of the El Niño phenomenon on the epidemiology of Bartonellosis in the Peruvian department of Ancash.  Trans R Soc Trop Med Hyg. 2004;98:116-124.

Ramírez Ramos A, Alayo E, Mendoza D, Leey J, Segovia M, Otoya C. Changes in the prevalence of H. pylori in Peru; 1985-2002 period in medium and upper socio-economic strata (translated from Spanish version).  Rev Gastroenterol Peru. 2003;23(2):92-8.

Rodríguez W, Watanabe-Yamamoto J, Ramírez Ramos A, Gilman HR, Rodríguez Ulloa C, Pareja Cruz A, Yushimito L, Alayo E, et al. Omeprazole, amoxicillin and clarithromycin in the treatment of helicobacterpylori, in 7 and 10-day regimens (translated from Spanish version). Rev Gastroenterol Peru. 2003 Jul-Sep;23(3):177-83.

Peinado J, Alayo E, Mendoza D, Rosas A, Nasarre C, Llanos F. Use of Geographic Information Systems to evaluate the association of asthmatic crisis in children living within factory-contaminated areas in the district of San Martin de Porres.1997-1998 (translated from Spanish version). Rev Peru Med Exp Salud Publica 2002; 19(3): 124-130.

Luy G, Maldonado G, Alayo E, Peinado J, Luy V. Clinical characteristics of colonic cancer. E. Rebagliati Martins Hospital, 1995-1999 (translated from Spanish version). Rev Gastroenterol Peru. 2001; 20:4: 406-413.

Cubillas R, Maguiña C, Saona P, Alayo E, Llanos E: Prevalence of Anti-Toxoplasma Gondii antibodies in pregnant women at the Cayetano Heredia National Hospital – February 1998 (translated from Spanish version). Boletín de la Sociedad Peruana de Medicina Interna. 2000;13(4):124.

Ramírez-Ramos A, Recavarren S, Arias Stella J, León-Barúa R, Gilman R, Watanabe E, Alayo E. Helicobacter pylori, chronic gastritis, gastric ulcer and duodenal ulcer: study in 1638 patients (translated from Spanish version). Rev Gastroenterol Peru. 1999; 19(3):196.

Ramírez-Ramos A, Gilman R, Recavarren S, León-Barùa R, Watanabe E, Arias Stella J, Alayo E. Contribution to the study of the epidemiology of Helicobacter pylori in Peru: analysis of 3005 cases (translated from Spanish version). Rev Gastroenterol Peru. 1999; 19(3):190.

Alzamora B, Tobaru L, Haro D, Chavez R, Alayo E. Clinical trial using Clotrimazol 1%, systemic Ketoconazol and sytemic Fluconazol in the treatment of mycotic keratitis (translated from Spanish version). Revista Peruana de Oftalmología. 1999;23(1):37.

Alayo E, Chavez J, Namisato C, Larco J, Reyes C, Leon Barua R, Sack B, Salazar E. Prevalence of lactose intolerance in Peruvian children and adults. In preparation.

Nasarre C, Mendoza C, Alayo E, Chumpitaz RM, Cabero D, Fuentes P, Gilman RH. Latent pulmonary tuberculosis in autopsied humans: molecular, bacteriologic and pathologic studies. In preparation.

Ramírez-Ramos A, Gilman HR, Watanabe-Yamamoto J, Takano-Moron J, Arias-Stella J, Yoshiwara Wakabayashi E, Rodríguez-Ulloa C, Miyagui Maeda J, Velapatino Cochachi B, Mendoza-Requena D, Alayo E, et al. Helicobacter pylori infection in a Japanese population in Lima, Peru. In preparation.

Thesis

Mortality predictive value of the index Cortisol/ Triodothyronine on the admission to the General Intensive Care Unit. Thesis of Medicine – Cayetano Heredia University. 1998.

Book

Ramirez Ramos A and Alayo E. Gastrointestinal alterations in the elderly (translated from Spanish version). Gerontology Topics. Varela, L  2nd Ed. UPCH, Lima. 2002;pp:200.

Abstracts and Presentations

Alayo E, Attar B, Abrahamian F. Cholestatic Hepatitis Associated with Hyperthyroidism, and Exacerbated by Methimazole Therapy. American College of Gastroenterology Annual Meeting 2007. Philadelphia, PA.

Smith CA, Alayo E, Fung S, Evans AT, Reilly BM, Mandelbaum S. Use of a Screening Tool by Medical Residents to Recognize and Treat Major Depression in Hospitalized Patients: A Controlled Trial. SGIM Annual Meeting, Los Angeles, 2006.

Alayo E, Smith CA, Mandelbaum S, Fung S, Evans AT. The test characteristics of a new depression Tool used by Medicine Residents evaluating Hospital Admissions. SGIM Annual Meeting, Los Angeles, 2006.

Attar BM, Halliburton C, Alayo E. Correlation of ultrasonography and histology in patients with steatosis. Gastroenterology. 2006;130:A-595.

Attar BM, Guthrie G, Alayo E, Orucevic A. Are Hispanics at increased risk for NASH?  Digestive Disease Week 2005, Chicago, IL.

Attar BM, Evans AT, Pandolfi G, Vladic F, Alayo E, Orucevic A, Reilly BM. Diabetes mellitus versus HIV co-infection: Which one leads to more fibrosis in HCV patients? Digestive Disease Week 2005, Chicago, IL.

Shi F, Ferrer K, Attar BM, Alayo E, Pandolfi G, Sekosan M, Orucevic A. Histophatology of the liver in untreated human immunodeficiency virus and hepatitis C (HIV/HCV) coinfected patients in a county hospital.  US and Canadian Academy of Pathology Annual Meeting. 2005.

Attar BM, Vladic F, Pandolfi G, Alayo E, Orucevic A. The impact of Diabetes Mellitus and Steatosis on Hepatic Fibrosis and Inflammation in HCV Patients. Annual Meeting of the American Society for the Study of Liver Diseases. 2004. Boston, MA.

Attar BM, Pandolfi G, Vladic F, Alayo E, Adeyemi O, Cotler S, Jensen D. Race as an important factor on the model construction for predicting HCV-related fibrosis. American College of Gastroenterology Annual Meeting 2004. Orlando, LA.

Attar BM, Alayo E, Pandolfi G, Adeyemi O, Cotler S, Jensen D. Factors implicated in receiving therapy in patients with Hepatitis C ± HIV co-infection in a lower socioeconomic group. American College of Gastroenterology Annual Meeting 2004. New Orleans, LA.

Attar BM, Pandolfi G, Vladic F, Alayo E, Orucevic A, Atten M. Prediction of HCV-related fibrosis and inflammation based on a constructed model. Digestive Disease Week  2004.  New Orleans, LA.

León-Barúa R, Recavarren S, Alayo E, Gilman R. Helicobacter pylori-associated chronic atrophic gastritis probably predisposing to severely dehydrating diarrheal disease by Vibrio Cholera. Annual Meeting of the American Society of Tropical Medicine and Hygiene. 2002. Denver, Colorado.

Ventosilla P, Huarcaya E, Alayo E, León F, Palacios A, Gutierrez P, Vidal S, Aron J. Influence of El Niño event on the transmission of malaria in Luciano Castillo & Colonna (Piura, Perú). Conference in Climate Variability and Change and Their Health Effects in the Caribbean. 2002. Barbados.

Alayo E, Huarcaya E, Peinado J, Llanos A. The Influence of the El Niño phenomenon on the epidemiology of Bartonellosis in the Peruvian Department of Ancash. Annual Meeting of the American Society of Tropical Medicine and Hygiene. 2001. Atlanta, Georgia.

Alayo E, Villena J, Contardo M. Mortality Predictive value of the index Cortisol / Triodothyronine on the admission to the General Intensive Care Unit. National Congress of Internal Medicine. 2000. Peru.

Alayo E, Villena J, Contardo M. Thyroid function in patients in the General Intensive Care Unit and its relation to mortality. International Scientific Medical Student Congress XIV – FELSOCEM. 1999. Panama.

Academic Affiliations / Activities

  • Medical Intern Representative, UPCH, 1999-2000
  • Member, Scientific Society of Medical Students, UPCH, 1999-2000
  • Student Representative, University Assembly, UPCH, 1998-2000
  • Founding Member, Medical Student Association, UPCH, 1998-2000
  • Student Representative, Council of the Faculty of Medicine, UPCH, 1997-1998

Other skills

  • Bilingual in Spanish and English.
  • Software skills include database and statistical packages, such as EPI INFO 6.04, SPSS 10.0, MAPINFO 4.12, and STATA v.8.0.

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